Pharmacology

About Department:

Department of Pharmacology is an important paraclinical department that renders academic services to undergraduate and postgraduate students and support patient related services to clinical departments by providing drug information and assisting Pharmacy in-charge in preparing hospital drug formulary. It imparts knowledge about Journey of the drugs starting from its origin, action, its movement in the body (pharmacokinetics) and its beneficial and hazardous effect on our body.

The Department is situated at first floor of college building and welcomes the students of II-year MBBS, II-year BDS and first year postgraduates of MD (Pharmacology). The department also provides teaching-learning support to B.Sc. (OT & AT) students.

The department is headed by Dr Usha Sadasivan, retired Dean of reputed Govt. Medical College with outstanding administrative & educational excellence record. She is having 31 years of teaching experience.  

The department has necessary teaching learning facilities for undergraduates as well as postgraduates as per MCI norms. The department has an animal house that was established in year 2014 to initiate research on small animals for postgraduate training. It is registered in 17/8/2015 and license is renewed (1818/GO/Ere/S/15/CPCSEA) on 4/12/2018. Facilities of animal house are available to all other departments as well as sister institutes. Students are trained about the animal experiments in Computer simulated model installed in central library.   

The department has Pharmacovigilance unit to support pharmacovigilance program. Postgraduates students daily visit the clinical departments, collect adverse drug reactions (ADR) and report it to our department. After causality assessment, report is sent to approved ADR monitoring centre. The department is very keen in creating awareness among students, faculties and hospital staff about adverse drug reactions. Every 2 monthly pharmacology department conducts awareness program about ADR and drug safety.

Department houses spacious museum with models developed by students about mechanism of action of drugs. Pharmacokinetics charts, charts with history of drugs, herbal medicine charts, various commonly used drugs, and different medical devices for understanding routes of drug administration are also displayed in the museum.

Department promotes students’ participatory activities by organising model /quiz / poster competition for the students in order to develop creativity and kindle their interest in Pharmacology. Postgraduates are motivated to conduct research other than dissertation with emphasis on Animal Research, Pharmacovigilance, Pharmacogenomics and Toxicology. Research aptitude of undergraduates is encouraged by undertaking ICMR-STS project. In last 3 years, two ICMR-STS projects have been accepted from our Department.

Research:

Total number of Publications: 17

1. In-Vitro Anthelmintic activity of Ethanolic leaf extract of Luffa Acutangula on Indian Earthworms PheretimaPosthuma
2. Pharmacokinetic interaction of Phosphorus on the treatment of sputum positive Pulmonary tuberculosis patients
3. Assessment of Hepatoprotective activity of SymplocosRacemosa bark againstparacetamol induced liver damage in rats and its possible mechanism of action
4. Antiulcer activity of Aqueous extract of WaltheriaIndica leaf against pyloric ligated ulcer model in rats
5. A Randomized Comparative Study of Efficacy and Safety of Epalrestat and Methylcobalamin in Patients with Diabetic Neuropathy
6. Scientific validation of antiurolithiatic activity of Luffa Acutangula root extract against Ethylene Glycol induced urolithiasis in Wistar albino rats
7. Evaluation of efficacy and safety of Gluosamine and Chondroition sulphate in Osteoarthritis of knee
8. Anxiolytic activity of aerial parts of WaltheriaIndica using experimental anxiety model
9. Prevalence of Hepatitis –B and hepatitis C co-infection in seropositive HIV individuals from tertiary care hospital
10. Prescribing pattern of anti-microbials in a tertiary care hospital
11. Cough suppressant and expectorant activities of ethanolic extract of PergulariaNaevia in mice model
12. Inhibition of cyclic adenosine 3′,5′-monophosphate (cAMP) in the generation of seizure threshold by potent specific phosphodiesterase (PDE-3) inhibitors
13. Carbamazepine induced steven Johnson syndrome
14. Assessment of Prescribing Pattern and cost analysis of Topical Steroids for skin Disorders in Dermatological Outpatient Department of a Tertiary care hospital
15. Assessment of Knowledge and Attitude towards alternative to animal experimentation in research and education among interns and post graduate medical students in a teaching hospital Tamilnadu, India
16. Proteasome Inhibitor: A Targeted Therapy
17. Haloperidol Induced Rabbit Syndrome

1. Department Research Lab
2. Pharmacy and Experimental Pharmacology Lab
3. Pharmacovigilance Centre
4. Animal House with full time veterinary Surgeon: for Animal Research
5. Clinical Pharmacology room:
6. Computer Simulated Model (as an alternative to animal experiment)
7. Museum: with adequate number of models, charts, specimens and drugs

1. Sl. No	Name of the Event	Date when organized	Total number of participants
   1	CME-Pharmacovigilance – Drug Sensitization & ADR Reporting	05.04.2017	96
   2	Poster competition	17.8.2017	101
   3	Workshop- Zebra Fish Promising Research Model	03.03.2018	43
   4	Model competition	29.10.2018	103
   5	CME- Recent Advances in Management of Drug Addiction	28.09.2018	86
   6	National Work-shop on Good Clinical Practice	02.04.2019	71
   7	CME-Pharmacovigilance – Drug Safety Signals	27.08.19	72
   8	Pharmacology Quiz Competition	26.11.2019	109

1. Sl. No.	Name of the Student	PG Guide	Co-guide	Duration	Year of dissertation acceptance	Year of Course completion
   1	Dr.P. Kalaiselvi	Dr. Purabi Roy	—————	3 years	2013	2016
   2	Dr. Lekshmanan	Dr. Purabi Roy	Dr. Swaminathan	3 years	2013	2016
   3	Dr. Sunil M Vishwasrao	Dr. Jacob Verghese	Dr. Sufala S Vishwasrao	3 years	2014	2017
   4	Dr. V.D.Deepti	Dr. Kavitha	—————	3 years	2015	2018
   5	Dr. Preeth	Dr. Jacob Verghese	Dr. V. Gopal Dass	3 years	2015	2018
   6	Dr. E. Akila	Dr. Jacob Verghese	Dr. Prathap	3 years	2016	2019
   7	Dr. Ganesh Kumar	Dr. Kavitha	—————	3 years	2016	2019

Undergraduates

Postgraduates